该研究表明，crispr-cas9是一种有用的工具，可用于识别新的药物靶点和开发治疗椎间盘退变的策略。 crispr-cas9系统利用向导RNA（gRNA）识别靶DNA序列。当发现匹配的DNA序列时，cas9蛋白会在正确的位置切割靶DNA，然后就有可能在DNA水平上进行外科手术来修复遗传疾病。

2019年5月12日讯/生物谷BIOON/---在一项新的研究中，来自美国布罗德研究所等研究机构的研究人员发现酿脓链球菌Cas9（SpCas9）的 ...

Bacteria-attacking viruses, known as bacteriophages, use small RNAs to disarm the CRISPR-Cas immune systems of bacteria. This discovery has now been documented by researchers at the University of ...

In the second new research review on this subject, Assistant Prof. Ibrahim Bitar, Department of Microbiology, Faculty of Medicine and University Hospital in Plzen, Charles University in Prague, Plzen, ...

CRISPR’s promise of curing diseases hit a setback when researchers discovered that AZD7648, a molecule designed to improve precision, also caused catastrophic hidden damage to DNA. Instead of perfect ...

CHICAGO, IL—A novel CRISPR/Cas-9-based gene-editing technique seems to safely diminish the production of a protein linked to worsening outcomes in patients with transthyretin (ATTR) amyloidosis ...

Genetic modifications in reproductive cells, such as eggs, sperm, or embryos, are commonly referred to as germline editing and are heritable. 1 CRISPR-Cas 9, which stands for clustered regularly ...

At the heart of every CRISPR reaction, whether naturally occurring in bacteria or harnessed by CRIPSR-Cas gene editing technology, is a strong molecular bond of a Cas protein via a guide RNA to its ...

OTTAWA, Nov. 19, 2020 (GLOBE NEWSWIRE) -- One of the most ground-breaking improvements in biology sector has its origins in the RNA-based defense system of bacteria, that encrypts CRISPR-associated ...