The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...

Scientists have created a live-cell DNA sensor that reveals how damage appears and disappears inside living cells, capturing ...

While most known types of DNA damage are fixed by our cells’ in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows. This means that ...

A novel technology combined with optical tweezer C-trap technology gives researchers new insight into DNA repair mechanisms. Researchers at the University of Pittsburgh (PA, USA) have developed a ...

In a quiet lab at Utrecht University, researchers have built a tool that lets you watch one of life’s most serious crises ...

Cedars-Sinai scientists have created a new experimental drug called TY1 that helps the body repair damaged DNA and restore ...

The findings may have important implications for diseases linked to mitochondrial dysfunction. A newly identified form of DNA damage inside mitochondria, the small structures that supply energy to our ...

Inside every human cell, tiny mitochondria quietly convert nutrients into usable energy, keeping organs running and immune ...

Unlike most cell types, which continuously divide, neurons have to last for the life of the organism. How do they do that? One way neurons stay healthy is by repairing their DNA as they transcribe it.

UC Riverside researchers identify a new mitochondrial DNA adduct that disrupts energy production and triggers stress-response ...