In all forms of gene therapy, DNA exerts its influence from within the nucleus. Recombinant events for viral delivery of plasmid DNA are permanent and alter the genomes of the affected cells and their ...

Researchers explore a basic building block used in the fabrication of many DNA nanoforms. Known as a Holliday junction, this nexus of two segments of double stranded DNA has been used to form ...

The fundamental organization of the DNA in active and inactive compartments arises immediately after fertilization of the oocyte, even before genes are activated. The discovery will lead to a better ...

DNA is the genetic material used by every living organism. But, in a few edge cases, the four bases of DNA—adenine, thymidine, cytosine, and guanine—undergo chemical modifications. And in viruses, ...

Tiny repeated stretches of DNA in your genome may quietly shape how your body works, how your brain develops and how you ...

DNA stands for Deoxyribonucleic Acid, the molecule that carries the genetic code of all living things. It’s found in every cell and determines everything from your looks to your body functions. In ...

A group led by researchers at Baylor College of Medicine has identified significant differences at the epigenetic level – the chemical tags in DNA that help regulate gene expression – between two ...

A breakthrough live-cell sensor makes DNA repair visible as it happens, unlocking new possibilities in biology and medicine.

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break-when both sides of the DNA helix are cut at once.